产品货号：
Z12126
中文名称：
Betatrophin/ANGPTL8抗体
英文名称：
Anti-Betatrophin/ANGPTL8 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Betatrophin/ANGPTL8 Antibody |
| 指标别名 | ANGPTL8;Betatrophin;C19orf80;LOC55908;PRO1185;PVPA599;td26 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | ANGPTL8 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human C19orf80 recombinant protein (Position:A22-A198).Human C19orf80 shares 74% amino acid (aa) sequence identity with mouse C19orf80. |
| 实际分子量 | 22KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ANGPTL8 (also known as lipasin,originally Betatrophin) is a protein that in humans is encoded by the C19orf80 gene.The gene for betatrophin lies on mouse chromosome 9 (gene symbol:Gm6484) and on human chromosome 19 (gene symbol:C19orf80).The encoded 22kDa protein contains an N-terminal secretion signal and two coiled-coil domains and is a member of the angiopoietin-like (ANGPTL) protein family.However,in contrast to other ANGPTL proteins,betatrophin lacks the C-terminal fibrinogen-like domain,and therefore it is an atypical member of the ANGPTL family.It shares with Angptl4 and Angptl3 the ability to inhibit the enzyme Lipoprotein lipase (LPL),and its hepatic overexpression causes elevation of circulating Triglyceride levels in mice.In mice betatrophin is secreted by the liver.It was hoped that betatrophin or its homolog in humans may provide an effective treatment for type 2 diabetes and perhaps even type I diabetes. |
| Uniprot ID | Q6UXH0 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
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